Glucagon is critical for normal glucose homeostasis and aberrant secretion of the secretion during hypoglycaemia, while paracrine signalling from beta- and 

Most of these factors secreted from adipose tissue act in an autocrine/paracrine manner to regulate adipocyte metabolism; upon secretion into the bloodstream, they act as endocrine signals at multiple distant sites to regulate energy homeostasis (Flier and Maratos-Flier 1998, Mohamed-Ali et al. 1998).

850 000 kr. Markus Lundgren, Lund. ALUMNI studien: Långtidsuppföljning av barn med hög  Avhandling: Autocrine/paracrine interactions moendocrine pancreasdulating hormone is a potent stimulus for glucagon secretion but not for insulin secretion. Glucagon is critical for normal glucose homeostasis and aberrant secretion of the secretion during hypoglycaemia, while paracrine signalling from beta- and  Search for dissertations about: "α-cell" · 1. α-Cell signalling in glucose-regulated glucagon secretion · 2. Paracrine control of glucagon secretion in the pancreatic α-  In Expt 2, oxytocin-induced PGF2alpha secretion was characterized on days 13 and 16 of the luteal phase in mares undergoing normal oestrous cycles (n=6) and  Glucose-lowering-induced stimulation of glucagon secretion thus corresponded to an elevation in cAMP that was independent of paracrine  studied in conscious rats during pentagastrin-stimulated gastric acid secretion. The animals were equipped with a chronic gastric fistula to measure acid  secretion of EPO for regulation of RBC produktion, and renin, for cortical.

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Losy F (1), Dai J, Pages C, Ginat M, Muscatelli-Groux B, Guinault AM, Rousselle E, Smedile G, Loisance D, Becquemin JP, Allaire E. However, paracrine regulators do not inhibit secretion below the basal rate , and glucagon secretion is maximally suppressed at glucose concentrations that are too low to stimulate insulin or somatostatin secretion (66, 77). These data point to a role for intrinsic regulation at low glucose concentrations. In this case, evidence supports a critical role for donor cell secretion of signaling molecules and trophic paracrine effects in the repair process. Transplantation of exogenous cells into damaged myocardium – also known as cellular cardiomyoplasty (CCM) – is a possible cell therapy for the treatment of several cardiac diseases.

Paracrine secretion of transforming growth factor-beta1 in aneurysm healing and stabilization with endovascular smooth muscle cell therapy. Losy F (1), Dai J, Pages C, Ginat M, Muscatelli-Groux B, Guinault AM, Rousselle E, Smedile G, Loisance D, Becquemin JP, Allaire E. However, paracrine regulators do not inhibit secretion below the basal rate , and glucagon secretion is maximally suppressed at glucose concentrations that are too low to stimulate insulin or somatostatin secretion (66, 77). These data point to a role for intrinsic regulation at low glucose concentrations.

"Paracrine delivery of therapeutic biologics"Sheena Smith, Department of as secretion by the tumor itself could provide high local concentrations where they 

1. J Vasc Surg. 2003 Jun;37 (6):1301-9. Paracrine secretion of transforming growth factor-beta1 in aneurysm healing and stabilization with endovascular smooth muscle cell therapy.

Jun 16, 2013 Here, we present evidence that the SASP can also induce paracrine senescence in normal cells both in culture and in human and mouse models 

The concept that glucagon secretion is regulated by paracrine processes is supported by reports that isolated α‐cells (in which intra‐islet insulin signalling is physically disrupted) respond inappropriately to elevation of glucose with stimulation of glucagon secretion 16, 17. Such a paracrine mechanism would explain the modest delay that separates glucose-stimulated insulin and somatostatin secretion .

in a paracrine manner via local diffusion in the intercellular spaces, but also systemically through its release into the local mucosal blood circulation; it inhibits acid secretion by acting on parietal cells. Nervous 2019-11-07 · Paracrine signaling cells secrete local mediators that affect surrounding cells in the direct immediate environment. Paracrine is local, so signaling molecules are destroyed rapidly if not taken up by the local target cells. Examples of Paracrine Signaling are blood clotting factors and nitric oxide.
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The animals were equipped with a chronic gastric fistula to measure acid  secretion of EPO for regulation of RBC produktion, and renin, for cortical. Short 100p. * reabsorbtion o secretion Paracrine substance -12 lokala messengers.

Accurate control of insulin release is of critical importance; too little insulin leads to diabetes, …. Inhibitory factor: somatostatin - acts on somatostatin-2 receptors on G cells. in a paracrine manner via local diffusion in the intercellular spaces, but also systemically through its release into the local mucosal blood circulation; it inhibits acid secretion by acting on parietal cells.
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Paracrine signaling cells secrete local mediators that affect surrounding cells in the direct immediate environment. Paracrine is local, so signaling molecules are destroyed rapidly if not taken up by the local target cells. Examples of Paracrine Signaling are blood clotting factors and nitric oxide.

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